Can you use the two parameters with Generic class in C#

Yes, You can use more than one type parameters in Generic class.For it you can use the parameters list with comma separated ( if you are new with Generics Read this article Generics in C#) . See the following example:

using System;
using System.Collections.Generic;
using System.Text;
namespace ConsoleApplication1
    public class GenTwoparam<T, S>
        T tempObj1;
        S tempObj2;
        public GenTwoparam(T obj1, S obj2)
            tempObj1 = obj1;
            tempObj2 = obj2;
        public void ShowTypes()
            Console.WriteLine("the type of first parameter is " + typeof(T) + " and value is " + tempObj1);
            Console.WriteLine("the type of first parameter is " + typeof(S) + " and value is " + tempObj2);
    class Program
        static void Main(string[] args)
            GenTwoparam<int, string> clsObj = new GenTwoparam<int, string>(15, "Welcome");

The output of the above program will be:

the type of first parameter is System.Int32 and value is 15
the type of first parameter is System.String and value is Welcome

From the above we create a GenTwoParam class that is declated with two parameters T and S:
public class GenTwoparam {}
and we create anew object of the GenTwoParam in the Class1 by providing the two both types as:
GenTwoparam clsObj = new GenTwoparam(15, “Welcome”);
on here T refers as int and S refers as string type or we can say T is the subsitute of the System.Int32 and S is the subsititute of the System.string.
We can also create the object of the genTwoParam with different type parameters such as:
GenTwoparam clsObj = new GenTwoparam(15.87, “Welcome”);